The Activated Partial Thromboplastin Time (APTT) plasma test evaluates the intrinsic and common pathways of the coagulation cascade. It is primarily used to investigate bleeding disorders, monitor patients on unfractionated heparin therapy, and assess preoperative coagulation status. Prolonged APTT results can indicate deficiencies in clotting factors (VIII, IX, XI, or XII), the presence of lupus anticoagulant, or liver dysfunction, while shortened times may reflect hypercoagulable states.
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