The Anti-Nuclear Antibody (ANA) test detects autoantibodies targeting nuclear components of cells, serving as a primary screening tool for autoimmune diseases. It is most commonly used in diagnosing systemic lupus erythematosus (SLE), but it is also relevant for conditions such as Sjögren’s syndrome, scleroderma, and mixed connective tissue disease. A positive ANA result often prompts further specific antibody testing to confirm diagnosis and guide treatment strategies.
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